MAPT Antibody

CAT: 0223-30-353Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-30-353Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MAPT is differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. The mutations in the gene have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.
NCBI Gene ID
4137
Swiss Prot
P10636-8
Accession Number
NP_005901
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MAPT.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store MAPT antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
46 kDa, 40 kDa, 79 kDa, 37 kDa
Applications Notes
MAPT antibody can be used for detection of MAPT by ELISA at 1:312500. MAPT antibody can be used for detection of MAPT by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
MAPT
NCBI Official Name
Microtubule-associated protein tau
NCBI Organism
Homo sapiens
Background Reference 01
Reynolds, M.R., (2006) Biochemistry 45 (13), 4314-4326.
Other Product Names
MAPT, DDPAC, FLJ31424, FTDP-17, MAPTL, MGC138549, MSTD, MTBT1, MTBT2, PPND, TAU
Tested Applications
ELISA, WB
Protein ID
6754638
Physical Properties
Liquid

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