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Stratifin Recombinant Protein

CAT: 0223-91-153Size: 0.05 mgDry Ice: NoHazardous: No
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CAT#:0223-91-153Size:0.05 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Stratifin (SFN) belongs to the 14-3-3 family of proteins that act as important regulators of intracelluar signal transduction through their ability to bind specific motifs phosphorylated on serine or threonine. There are at least seven isoforms that have been identified in mammals (beta, gamma, epsilon, sigma, zeta, tau and eta) . SFN can detected in many tissues, highly expressed in stratified squamous keratinizing epithelium. SFN is indicated as an epithelial cell marker and serves as a tumor suppressor whose expression can be down regulated by methylation. In addition, SFN plays a key role in maintaining the G2 checkpoint in cells and preventing mitotic death.
CAS Number
9000-83-3
NCBI Gene ID
2810
Swiss Prot
P31947
Accession Number
P31947
Tag
Tag Free
Type
Recombinant Proteins
Source
E. coli
Field of Research
Cancer, Neuroscience, Signal Transduction, Other
Buffer
Lyophilized from a 0.2 um filtered solution of 20mM PB, 250mM NaCl, 1mM EDTA, 1mM DTT, pH 7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Calculated Molecular Weight
27.77 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Stratifin
NCBI Organism
Homo sapiens
Other Product Names
14-3-3 Protein Sigma, Epithelial Cell Marker Protein 1, Stratifin, SFN, HME1
Species
Human
Protein ID
618854972
Physical Properties
Lyophilized

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