Pentraxin 2 Recombinant Protein

• Background:

  Serum Amyoid P Component (SAP) is a monomeric 25 kDa secreted serum glycoprotein that belongs to the pentraxins family. The members of pentaxin superfamily be characterised by calcium dependent ligand binding and distinctive flattened beta -jellyroll structure similar to that of the legume lectins. SAP is a non-fibrillar component, it can interact with DNA and histones. It regulates the solubility of amyloid fibrils and protects them from degradation by proteolytic enzymes and phagocytic cells. SAP scavenge nuclear material released from damaged circulating cells. It has been proposed that SAP may function as an opsonin for a variety of ligands including autoantigens, apoptotic cells, chromatin and micro-organisms.

• NCBI Gene ID:

  325

• Swiss Prot:

  P02743

• Accession Number:

  P02743

• Tag:

  C-6 His tag

• Type:

  Recombinant Proteins

• Source:

  Human Cells

• Field of Research:

  Neuroscience

• Buffer:

  Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

• Shipping Conditions:

  Room Temp

• Calculated Molecular Weight:

  24.2 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Amyloid P component, serum

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Serum Amyloid P-Component, SAP, 9.5S Alpha-1-Glycoprotein, APCS, PTX2

• Species:

  Human

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3