SERPINA3 Recombinant Protein

• Background:

  Serpin A3 is also known as Alpha-1-antichymotrypsin (ACT or AACT), Cell growth-inhibiting gene 24/25 protein, which belongs to the serpin family. Serpin A3 can bind DNA. Although its physiological function is unclear, it can inhibit neutrophil cathepsin G and mast cell chymase, both of which can convert angiotensin-1 to the active angiotensin-2.

• NCBI Gene ID:

  12

• Swiss Prot:

  P01011

• Accession Number:

  AAH03559

• Tag:

  His Tag

• Type:

  Recombinant Proteins

• Source:

  HEK293 cells

• Field of Research:

  Cell Cycle, Neuroscience, Obesity, Signal Transduction

• Purity:

  >95% as determined by SDS-PAGE.

• Buffer:

  20 mM HEPES, 150 mM NaCl, pH 7.5

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.

• Calculated Molecular Weight:

  46 kDa

• Applications Notes:

  This recombinant protein can be used for WB. For research use only.

• NCBI Official Name:

  Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Rubin H., et al., 1990, J. Biol. Chem. 265:1199-1207.

• Background Reference 02:

  Kroczynska B., et al., 2004, J. Biol. Chem. 279:11432-11443.

• Background Reference 03:

  Liu T., et al., 2005, J. Proteome Res. 4:2070-2080.

• Other Product Names:

  SERPINA3, ACT, AACT, GIG24, GIG25

• Tested Applications:

  WB

• Species:

  Human

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3