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SERPINA3 Antibody

CAT: 0223-62-816Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-62-816Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
SERPINA3 is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease.
NCBI Gene ID
12
Swiss Prot
P01011
Accession Number
P01011
Host
Rabbit
Reactivity
Human
Immunogen
This SERPINA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 282-310 amino acids from the C-terminal region of human SERPINA3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Neuroscience
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
48 kDa
Fragment
Rabbit Ig
Symbol
SERPINA3
NCBI Official Name
Alpha-1-antichymotrypsin
NCBI Organism
Homo sapiens
Background Reference 01
Abraham, C.R., Shirahama, T. Neurobiol. Aging 11 (2), 123-129 (1990)
Background Reference 02
Baumann, U., Huber, R. J. Mol. Biol. 218 (3), 595-606 (1991)
Background Reference 03
Desrochers, P.E., Mookhtiar, K. J. Biol. Chem. 267 (7), 5005-5012 (1992)
Other Product Names
Alpha-1-antichymotrypsin, ACT, Cell growth-inhibiting gene 24/25 protein, Serpin A3, Alpha-1-antichymotrypsin His-Pro-less, SERPINA3, AACT
Tested Applications
WB, Flow
Protein ID
112874
Physical Properties
Liquid

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