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ADSF Recombinant Protein

CAT: 0223-92-448Size: 0.05 mgDry Ice: NoHazardous: No
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CAT#:0223-92-448Size:0.05 mg
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Background
Resistin known as adipose tissue-specific secretory factor (ADSF) or C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein (XCP1) that seems to suppress insulin ability to stimulate glucose uptake into adipose cells. The length of the resistin pre-peptide in human is 108 amino acid residues and in the mouse and rat it is 114 aa; the molecular weight is ~12.5 kDa. Resistin is a cytokine whose physiologic role has been the subject of much controversy regarding its involvement with obesity and type II diabetes mellitus (T2DM) . Resistin has been shown to cause "high levels of 'bad' cholesterol (low-density lipoprotein or LDL), increasing the risk of heart disease, resistin increases the production of LDL in human liver cells and also degrades LDL receptors in the liver. Potentially links obesity to diabetes.
CAS Number
9000-83-3
NCBI Gene ID
56729
Swiss Prot
Q9HD89
Accession Number
Q9HD89
Tag
C-Fc tag
Type
Recombinant Proteins
Source
Human Cells
Field of Research
Chemokines & Cytokines, Obesity, Signal Transduction, Other
Buffer
Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Calculated Molecular Weight
36.8 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Resistin
NCBI Organism
Homo sapiens
Other Product Names
Adipose tissue-specific secretory factor, C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein, Cysteine-rich secreted protein A12-alpha-like 2, Cysteine-rich secreted protein, FIZZ3ADSF, FIZZ3, Resistin
Species
Human
Physical Properties
Lyophilized