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PHS Recombinant Protein

CAT: 0223-91-226Size: 0.05 mgDry Ice: YesHazardous: No
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CAT#:0223-91-226Size:0.05 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Pterin-4- alpha-Carbinolamine Dehydratase (PCBD1) is the founding member of the Pterin-4- alpha-Carbinolamine Dehydratase Family. PCBD1 is involved in Tetrahydrobiopterin biosynthesis. It seems to prevent the formation of 7-Pterins and accelerate the formation of Quinonoid-BH2. Furthermore, PCBD1 regulates the homodimerization of the transcription factor Hepatocyte Nuclear Factor 1 (HNF1) and enhances its transcriptional activity. Defects in PCBD1 are the cause of BH4-Deficient Hyperphenylalaninemia Type D (HPABH4D) . HPABH4D is characterized by the excretion of 7-substituted Pterins in the urine of affected patients.
CAS Number
9000-83-3
NCBI Gene ID
5092
Swiss Prot
P61457
Accession Number
P61457
Tag
N-6 His tag
Type
Recombinant Proteins
Source
E. coli
Buffer
Supplied as a 0.2 um filtered solution of 20mM TrisHCl, 150mM NaCl, 1mM DTT, pH 8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Shipping Conditions
Dry Ice
Calculated Molecular Weight
14.2 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Pterin-4 alpha-carbinolamine dehydratase 1
NCBI Organism
Homo sapiens
Other Product Names
Pterin-4-Alpha-Carbinolamine Dehydratase, PHS, 4-Alpha-Hydroxy-Tetrahydropterin Dehydratase, Dimerization Cofactor of Hepatocyte Nuclear Factor 1-Alpha, DCoH, Dimerization Cofactor of HNF1, Phenylalanine Hydroxylase-Stimulating Protein, Pterin Carbinolamine Dehydratase, PCD, PCBD1, PCBD
Species
Human
Physical Properties
Liquid

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