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VAP-1 Recombinant Protein

CAT: 0223-40-576-01Size: 0.002 mgDry Ice: NoHazardous: No
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CAT#:0223-40-576-01Size:0.002 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
VAP-1 is a type II membrane cell adhesion protein belonging to the copper/topaquinone oxidase family. It is primarily expressed on the high endothelial venules of peripheral lymph nodes and on hepatic endothelia. VAP-1 can catalyze the oxidative deamination of low molecular weight amines, and plays an important role in the migration of lymphocytes to inflamed tissue. Inhibition of VAP-1 can protect against inflammation related damage to certain injured tissues. Additionally, VAP-1 can function as a significant prognostic marker for certain cancers and cardiovascular diseases. Recombinant VAP-1 is a mixture of monomeric and disulfide linked homodimeric forms of a 737 amino acid polypeptide corresponding to amino acids 27 to 763 of the VAP-1 precursor.
NCBI Gene ID
8639
Swiss Prot
Q16853
Accession Number
NP_001264660.1
Type
Recombinant Proteins
Source
CHO cells
Field of Research
Cancer, Neuroscience, Signal Transduction
Purity
Greater than 95% by SDS-PAGE gel and HPLC analyses.
Shipping Conditions
Room Temp
Storage Conditions
The lyophilized VAP-1 recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted VAP-1 stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing VAP-1 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
NCBI Official Name
Amine oxidase, copper containing 3
NCBI Organism
Homo sapiens
Other Product Names
HPAO, SSAO, VAP1, VAP-1, Membrane primary amine oxidase, Copper amine oxidase
Species
Human
Protein ID
480306390
Physical Properties
Lyophilized

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