Prostaglandin-D2 Synthase Recombinant Protein

• Background:

  Prostaglandin-H2 D-Isomerase (PTGDS) belongs to the Lipocalin family of calycin superfamily. PTGDS is preferentially expressed in the brain. PTGDS catalyzes the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation. PTGDS is involved in a variety of CNS functions, such as sedation, REM sleep and PGE2-induced allodynia, and may have an anti-apoptotic role in oligodendrocytes. PTGDS binds small non-substrate lipophilic molecules and may act as a scavenger for harmful hydrophopic molecules and a secretory retinoid and thyroid hormone transporter. It possibly participates in development and maintenance of the blood-brain, blood-retina, blood-aqueous humor, blood-testis barrier, the central nervous system and male reproductive system.

• NCBI Gene ID:

  5730

• Swiss Prot:

  P41222

• Accession Number:

  P41222

• Tag:

  C-6 His tag

• Type:

  Recombinant Proteins

• Source:

  Human Cells

• Field of Research:

  Signal Transduction

• Buffer:

  Supplied as a 0.2 um filtered solution of 20mM TrisHCl,150mM NaCl,10%Glycerol, pH7.5. It is not recommended to reconstitute to a concentration less than 100 ug/ml.

• Shipping Conditions:

  Dry Ice

• Calculated Molecular Weight:

  19.7 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Prostaglandin D2 synthase

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Prostaglandin-H2 D-Isomerase, Beta-Trace Protein, Cerebrin-28, Glutathione-Independent PGD Synthase, Lipocalin-Type Prostaglandin-D Synthase, Prostaglandin-D2 Synthase, PGD2 Synthase, PGDS, PGDS2, PTGDS, PDS

• Species:

  Human

• Physical Properties:

  Liquid

• CAS Number:

  9000-83-3