TEM7 Recombinant Protein

CAT: 0223-91-479Size: 0.05 mgDry Ice: NoHazardous: No
CAT#:0223-91-479Size:0.05 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Plexin Domain-Containing Protein 1 (PLXDC1) is a single-pass type I membrane protein that belongs to the plexin family. Secreted PLXDC1 is localized predominantly at the tight junctions of vascular endothelial cells and to a lesser extent at the luminal surface of vascular endothelial cells. PLXDC1 is expressed in fibrovascular membrane with increased expression in individuals with proliferative diabetic retinopathy. It can detect in endothelial cells from colorectal cancer, and in endothelial cells from primary cancers of the lung, liver, pancreas, breast and brain. PLXDC1 interacts with NID1 and may also interact with CTTN. It plays a important role in endothelial cell capillary morphogenesis, the proliferation and maintenance of neovascular endothelial cells in the formation of fibrovascular membranes (FVMs) .
CAS Number
9000-83-3
NCBI Gene ID
57125
Swiss Prot
Q8IUK5
Accession Number
Q8IUK5
Tag
C-6 His tag
Type
Recombinant Proteins
Source
Human Cells
Field of Research
Homeostasis
Buffer
Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, 5% Threhalose, pH 7.2. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Calculated Molecular Weight
46.53 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Plexin domain containing 1
NCBI Organism
Homo sapiens
Other Product Names
Plexin Domain-Containing Protein 1, Tumor Endothelial Marker 3, Tumor Endothelial Marker 7, PLXDC1, TEM3, TEM7
Species
Human
Protein ID
929654682
Physical Properties
Lyophilized