PEDF Recombinant Protein

• Background:

  Pigment epithelium-derived factor (PEDF) is a 47 kDa secreted glycoprotein that belongs to the non-inhibitory serpin family group. PEDF is widely expressed in adult and foetal tissues, including brain, spinal cord, plasma, bone, prostate, pancreas, heart and lung. PEDF acts as an angiogenesis inhibitor with neurotrophic, immunomodulation and antitumor properties. It functions as anti-angiogenic agent by counterbalancing the proangiogenic effect of VEGF. PEDF is one of the most abundant proteins released by adipocytes and induces insulin resistance in adipocytes and human skeletal muscle cells. Recently, it has been reported that PEDF is sufficient to maintain the self-renewal of pluripotent human embryonic stem cells.

• NCBI Gene ID:

  5176

• Swiss Prot:

  O75888

• Accession Number:

  P36955

• Tag:

  DDDDK Tag

• Type:

  Recombinant Proteins

• Source:

  CHO cells

• Field of Research:

  Cancer, Immunology, Innate Immunity, Neuroscience, Obesity, Signal Transduction, Stem Cell

• Concentration:

  0.1mg/ml after reconstitution.

• Buffer:

  Contains PBS. Reconstitute with 100 μ l sterile distilled water.

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  Stable for at least 6 months after receipt when stored at -20˚ C.

• Applications Notes:

  This recombinant proteins is for research use only.

• NCBI Official Name:

  Serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Pigment Epithelium-derived Factor, Cell Proliferation-inducing Gene 35 Protein, EPC-1, Serpin F1

• Species:

  Human

• Protein ID:

  39725934

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3