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PI4KB Recombinant Protein

CAT: 0223-91-682Size: 0.05 mgDry Ice: YesHazardous: No
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CAT#:0223-91-682Size:0.05 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Phosphatidylinositol 4-Kinase beta (PI4KB) belongs to the PI3/PI4-kinase family and Type III PI4K subfamily. PI4KB contains one PI3K/PI4K domain and one PIK helical domain. It is highly expressed in heart, skeletal muscle, pancreas, testis and ovary, ; it is lowly expressed in liver tissue. PI4KB kinase activity can be inhibited by wortmannin, and increased by interacting with NCS1/FREQ. PI4KB phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol-1,4,5, -trisphosphate (PIP) . In addition, PI4KB may regulate Golgi disintegration/reorganization during mitosis.
CAS Number
9000-83-3
NCBI Gene ID
5298
Swiss Prot
Q9UBF8-2
Accession Number
Q9UBF8-2
Tag
C-6 His tag
Type
Recombinant Proteins
Source
Human Cells
Field of Research
Obesity, Signal Transduction
Buffer
Supplied as a 0.2 um filtered solution of 25mM Tris.HCl, pH7.3,100mM glycine,10%glycerol. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Shipping Conditions
Dry Ice
Calculated Molecular Weight
90.8 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Phosphatidylinositol 4-kinase beta
NCBI Organism
Homo sapiens
Other Product Names
Phosphatidylinositol 4-Kinase Beta, PI4K-Beta, PI4KBeta, PtdIns 4-Kinase Beta, NPIK, PI4K92, PI4KB, PIK4CB
Species
Human
Physical Properties
Liquid

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