PPIase Recombinant Protein

• Background:

  Peptidyl-Prolyl Cis-Trans Isomerase-Like 1 (PPIase) belongs to the cyclophilin-type PPIase family. PPIases can accelerate the folding of proteins and catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. PPIase is a ubiquitous protein and has highly expression in heart , skeletal and muscle. PPIase contains a PPIase cyclophilin-type domain and four Cyclosporin A binding regions. PPIase might play an important role in proliferation of cancer cells through modulation of phosphorylation of stathmin. It is suggested that PPIase can act as as a novel molecular target for colon-cancer therapy.

• NCBI Gene ID:

  51645

• Swiss Prot:

  Q9Y3C6

• Accession Number:

  Q9Y3C6

• Tag:

  N-6 His tag

• Type:

  Recombinant Proteins

• Source:

  E. coli

• Field of Research:

  Immunology, Signal Transduction

• Buffer:

  Supplied as a 0.2 um filtered solution of 20mM TrisHCl, pH 8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.

• Shipping Conditions:

  Dry Ice

• Calculated Molecular Weight:

  20.4 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Peptidylprolyl isomerase like 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Peptidyl-Prolyl Cis-Trans Isomerase-Like 1, PPIase, Rotamase PPIL1, PPIL1, CYPL1

• Species:

  Human

• Physical Properties:

  Liquid

• CAS Number:

  9000-83-3