FKBP4 Recombinant Protein

• Background:

  Peptidyl-prolyl cis-trans isomerase FKBP4 (PPIase FKBP4) is also known as immunophilin FKBP52. FKBP4 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP4 has high structural and functional similarity to FK506-binding protein 1A (FKBP1A), but unlike FKBP1A, this protein does not have immunosuppressant activity when complexed with FK506. FKBP4 interacts with interferon regulatory factor-4 and plays an important role in immunoregulatory gene expression in B and T lymphocytes.

• NCBI Gene ID:

  2288

• Swiss Prot:

  Q02790

• Accession Number:

  AAH01786

• Tag:

  His Tag & PA Tag

• Type:

  Recombinant Proteins

• Source:

  HEK293 cells

• Field of Research:

  Other

• Buffer:

  50 mM Tris, 100 mM Glycine, pH7.5

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.

• Calculated Molecular Weight:

  55.1 kDa

• Applications Notes:

  This recombinant protein can be used for WB. For research use only.

• NCBI Official Name:

  FK506 binding protein 4, 59kDa

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Tai P.-K.K., et at., 1992, Science 256:1315-1318.

• Background Reference 02:

  Shim S., et al., 2009, Neuron 64:471-483.

• Other Product Names:

  FKBP4, FKBP52

• Tested Applications:

  WB

• Species:

  Human

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3