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LYPD3 Recombinant Protein

CAT: 0223-91-440Size: 0.05 mgDry Ice: NoHazardous: No
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CAT#:0223-91-440Size:0.05 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Ly6/PLAUR domain containing3 (LYPD-3) is a GPI-linked protein. The structure of LYPD-3 is similar to the urokinasetype plasminogen activator receptor (uPAR) . LYPD-3 is a 6 -100 kDa molecule with variable cell type-specific N-O-linked glycosylation, mature human LYPD-3 contains two uPAR/Ly6 domains and a Ser/Thr/Pro-rich (STP) region includes a protease sensitive site . The interaction of LYPD-3 with Laminin 1 and 5 on neighboring cells promotes the adhesion, spreading, and migration of tumor cells. LYPD-3 additionally interacts with Galectin-3 and the anterior gradient proteins AG-2 and AG-3. LYPD-3 overexpression in non-small cell lung cancer is predictive of increased mortality.
CAS Number
9000-83-3
NCBI Gene ID
27076
Swiss Prot
O95274
Accession Number
O95274
Tag
C-6 His tag
Type
Recombinant Proteins
Source
Human Cells
Field of Research
Cancer, Other
Buffer
Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Calculated Molecular Weight
27.89 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
LY6/PLAUR domain containing 3
NCBI Organism
Homo sapiens
Other Product Names
Ly6/PLAUR Domain-Containing Protein 3, GPI-Anchored Metastasis-Associated Protein C4.4A Homolog, Matrigel-Induced Gene C4 Protein, MIG-C4, LYPD3, C4.4A
Species
Human
Physical Properties
Lyophilized

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