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NGAL Recombinant Protein

CAT: 0223-92-610Size: 0.05 mgDry Ice: YesHazardous: No
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CAT#:0223-92-610Size:0.05 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Lipocalin-2, also known as Neutrophil Gelatinase-Associated Lipocalin (NGAL), is a secretory protein of the lipocalin superfamily. Lipocalin-2 contains a signal peptide that enables it to be secreted and form complexes with matrix metalloproteinase-9 (MMP-9) through disulfide bonds. Similar to other lipocalin family members, Lipocalin-2 is involved in diverse cellular processes, including the transport of small hydrophobic molecules, protection of MMP-9 from proteolytic degradation, and cell signaling. Furthermore, Lipocalin-2 can tightly bind to bacterial siderophore through a cell surface receptor, possibly serving as a potent bacteriostatic agent by sequestering iron, regulating innate immunity and protecting kidney epithelial cells from ischemia–reperfusion injury. This protein is mainly expressed in neutrophils and in lower levels in the kidney, prostate, and epithelia of the respiratory and alimentary tracts.Recent evidence also suggests its role as a biomarker for renal injury and inflammation.
CAS Number
9000-83-3
NCBI Gene ID
16819
Swiss Prot
P11672
Accession Number
P11672
Tag
C-Fc tag
Type
Recombinant Proteins
Source
Human Cells
Field of Research
Cancer
Buffer
Supplied as a 0.2 um filtered solution of 20mM MES, 150mM NaCl, 10% Glycerol, pH 5.5. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Shipping Conditions
Dry Ice
Calculated Molecular Weight
48 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Lipocalin 2
NCBI Organism
Mus musculus
Other Product Names
Neutrophil gelatinase-associated lipocalin, NGAL, Lipocalin-2, SV-40-induced 24P3 protein, Siderocalin LCN2, p25, LCN2
Species
Mouse
Physical Properties
Liquid

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