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PSA Recombinant Protein

CAT: 0223-92-336Size: 0.05 mgDry Ice: YesHazardous: No
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CAT#:0223-92-336Size:0.05 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
KLK3, also known as APS, is short for Prostate-specific antigen. It is a 261 aa. protein which belongs to the peptidase S1 family and Kallikrein subfamily. This protein has 5 isforms produced by alternative splicing. It is a secreted protein and can forms a heterodimer with SERPINA5 which can inhibit its activity. KLK3 is also strongly inhibited by Zn2+, 100 times more abundant in semen than in serum. This inhibition is relieved by exposure to semenogelins, which are avid zinc binders. KLK3 can hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum.
CAS Number
9000-83-3
NCBI Gene ID
354
Swiss Prot
P07288
Accession Number
P07288
Tag
C-6 His tag
Type
Recombinant Proteins
Source
Human Cells
Field of Research
Cancer, Cell Cycle, Immunology, Neuroscience, Signal Transduction, Other
Buffer
Supplied as a 0.2 um filtered solution of 20mM TrisHcl, 150mM NaCl,1mM CaCl2, pH7.5. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Shipping Conditions
Dry Ice
Calculated Molecular Weight
27.1 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Kallikrein related peptidase 3
NCBI Organism
Homo sapiens
Other Product Names
Prostate-specific antigen, PSA, Gamma-seminoprotein, Kallikrein-3, P-30 antigen, Semenogelase, KLK3, APS, Kallikrein 3, KLK3
Species
Human
Physical Properties
Liquid

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