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IL-35 Recombinant Protein

CAT: 0223-92-680Size: 0.05 mgDry Ice: NoHazardous: No
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CAT#:0223-92-680Size:0.05 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Interleukin-35 is a newest and potent suppressive cytokine of the IL-12 family. Unlike other members of the IL-12 family which are produced mainly by antigen-presenting cells (APCs), IL-35 has been identified as a potentially immunosuppressive cytokine primarily produced by regulatory T (Treg) cells, and to a lesser extent by activated dendritic cells and macrophages. IL-35 is composed of the IL-12 p35 subunit and the IL-27 Epstein–Barr virus-induced protein 3 (EBI3) subunit. IL-35 plays an important role in many disease models and has been recently shown to have additional functions aside from inhibition of proliferation, including inducing its own expression in non-Treg cells.
CAS Number
9000-83-3
NCBI Gene ID
10148;3592
Swiss Prot
Q14213, P29459
Accession Number
Q14213, P29459
Tag
C-Fc tag
Type
Recombinant Proteins
Source
Human Cells
Field of Research
Chemokines & Cytokines
Buffer
Lyophilized from a 0.2 um filtered solution of PBS, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Calculated Molecular Weight
73.9 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Epstein-Barr virus induced 3; interleukin 12A
NCBI Organism
Homo sapiens
Other Product Names
Interleukin 35, IL35, hIL35
Species
Human
Physical Properties
Lyophilized

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