Interferon Regulatory Factor 5 Recombinant Protein

• Background:

  Interferon Regulatory Factor 5 (IRF5) is a member of the IRF family. It contains one IRF tryptophan pentad repeat DNA-binding domain. IRF5 shuttles between the nucleus and the cytoplasm. IRF5 can form homodimer when it is phosphorylated. IRF5 functions as a transcription factor involved in the induction of interferons IFNA and INFB and inflammatory cytokines upon virus infection. Genetic variations in IRF5 are associated with susceptibility to systemic lupus erythematosus type 10. In addition, the genetic variations wil result in susceptibility to rheumatoid arthritis.

• NCBI Gene ID:

  3663

• Swiss Prot:

  Q13568

• Accession Number:

  Q13568

• Tag:

  C-6 His tag

• Type:

  Recombinant Proteins

• Source:

  E. coli

• Field of Research:

  Apoptosis, Immunology

• Buffer:

  Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

• Shipping Conditions:

  Room Temp

• Calculated Molecular Weight:

  57.1 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Interferon regulatory factor 5

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Interferon Regulatory Factor 5, IRF-5, IRF5

• Species:

  Human

• Protein ID:

  767904139

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3