IFNAR 1 Recombinant Protein

• Background:

  Interferon alpha/beta receptor 1 (IFNAR1) is also known as Cytokine receptor class-II member 1, Cytokine receptor family 2 member 1 (CRF2-1), Type I interferon receptor 1, IFNAR, which belongs to the type II cytokine receptor family. IFNAR1 /IFNAR contains four fibronectin type-III domains. IFNAR1 associates with IFNAR2 to form the type I interferon receptor. IFNAR1 is receptor for interferons alpha and beta. IFNAR1 can transduce IFNB signals without the help of IFNAR2, and not activating the Jak-STAT pathway.

• NCBI Gene ID:

  3454

• Swiss Prot:

  P17181

• Accession Number:

  NP_000620

• Tag:

  C-Fc Tag

• Type:

  Recombinant Proteins

• Source:

  HEK293 cells

• Field of Research:

  Cancer, Immunology, Signal Transduction

• Purity:

  85% (rh IFNAR1 /IFNAR Fc Chimera) and 13% (Human IgG1 Fc fragment) as determined by SDS-PAGE.

• Buffer:

  Tris with Glycine, Arginine and NaCl, pH7.5

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.

• Calculated Molecular Weight:

  73.8 kDa

• Applications Notes:

  This recombinant protein can be used for WB. For research use only.

• NCBI Official Name:

  Interferon (alpha, beta and omega) receptor 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Colamonici O., et al., 1994, Mol. Cell. Biol. 14:8133-8142.

• Background Reference 02:

  Li X., et al., 1997, Mol. Cell. Biol. 17:2048-2056.

• Background Reference 03:

  Russell-Harde D., et al., 1999, Biochem. Biophys. Res. Commun. 255:539-544.

• Other Product Names:

  IFNAR1, IFNAR, CRF2-1, IFN-R-1, IFNAR-1

• Tested Applications:

  WB

• Species:

  Human

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3