Hyaluronidase-1 Recombinant Protein

• Background:

  Hyaluronidase-1 (HYAL1) is a secreted lysosomal hyaluronidase that belongs to the glycosyl hydrolase 56 family. HYAL1 contains one EGF-like domain and is highly expressed in the liver, kidney, and heart, but it is weakly expressed in the lung, placenta, and skeletal muscle. HYAL1 is thought to be involved in cell proliferation, migration, and differentiation. It may play a role in promoting tumor progression and blocking the TGFB1-enhanced cell growth. Mutations in HYAL1 are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency.

• NCBI Gene ID:

  3373

• Swiss Prot:

  Q12794

• Accession Number:

  Q12794

• Tag:

  C-6 His tag

• Type:

  Recombinant Proteins

• Source:

  Human Cells

• Field of Research:

  Cancer, Signal Transduction

• Buffer:

  Supplied as a 0.2 um filtered solution of 20mM TrisHCl, 150mM NaCl, 10%Glycerol, pH7.5. It is not recommended to reconstitute to a concentration less than 100 ug/ml.

• Shipping Conditions:

  Dry Ice

• Calculated Molecular Weight:

  47.18 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Hyaluronoglucosaminidase 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Hyaluronidase-1, Hyal-1, Hyaluronoglucosaminidase-1, Lung Carcinoma Protein 1, LuCa-1, HYAL1, LUCA1

• Species:

  Human

• Protein ID:

  767904139

• Physical Properties:

  Liquid

• CAS Number:

  9000-83-3