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ICOS Recombinant Protein

CAT: 0223-91-826Size: 0.05 mgDry Ice: NoHazardous: No
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CAT#:0223-91-826Size:0.05 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Inducible T-cell costimulator, also known as activation-inducible lymphocyte immunomediatory molecule, CD278, AILIM, CVID1 and ICOS, belongs to the CD28 and CTLA4 cell surface receptor family.. ICOS contains one Ig-like V-type domain and exsits as a homodimer with disulfide-linked. ICOS is highly expressed on tonsillar T-cellsand can be induced by PMA and ionomycin, ICOS plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation. Defects in ICOS are the cause of immunodeficiency common variable type 1, which is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antige
CAS Number
9000-83-3
NCBI Gene ID
29851
Swiss Prot
Q9Y6W8
Accession Number
Q9Y6W8
Tag
C-Fc tag
Type
Recombinant Proteins
Source
Human Cells
Field of Research
Immunology
Buffer
Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4 . It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Calculated Molecular Weight
40.8 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Inducible T-cell co-stimulator
NCBI Organism
Homo sapiens
Other Product Names
Inducible T-cell costimulator, activation-inducible lymphocyte immunomediatory molecule, CD278, AILIM, CVID1, ICOS
Species
Human
Physical Properties
Lyophilized

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