CD278 [ICOS] non-lytic Recombinant Protein

• Background:

  CD278, also called inducible costimulator (ICOS) or CRP1 (CD28-related protein-1), is a member of the growing CD28 family of immune costimulatory receptors. Other family members are CD28, CTLA-4 and PD-1. ICOS is expressed on most CD45RO+ cells. ICOS expression is upregulated within approximately 24-48 hours of activation on Th primed cells. B7-H2, a member of the B7 family of costimulatory ligands, has been identified as the ICOS ligand. The B7-H2/ICOS interaction appears to play roles in T cell dependent B cell activation and Th differentiation.

• NCBI Gene ID:

  29851

• Swiss Prot:

  P10145

• Accession Number:

  NP_036224

• Tag:

  Fc Tag

• Type:

  Recombinant Proteins

• Source:

  CHO cells

• Field of Research:

  Immunology

• Buffer:

  Lyophilized from 0.2um-filtered solution in PBS. Reconstitute at 100 μ g/ml in sterile PBS.

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  Stable for at least 1 year after receipt when stored at -20˚ C. Working aliquots are stable for up to 3 months when stored at -20˚ C.

• Applications Notes:

  This recombinant proteins is for research use only.

• NCBI Official Name:

  Inducible T-cell co-stimulator

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  ICOS, Inducible T Cell Costimulator, CRP1, CD28-related Protein-1, AILIM

• Species:

  Human

• Protein ID:

  15029518

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3