PDGF-Associated Protein Recombinant Protein

• Background:

  Human PAP, also known as 28 kDa heat- and acid-stable phosphoprotein, PDGF-associated protein, PDGFA-associated protein 1, PDAP1, HASPP28, is a protein which belongs to the PDAP1 family. The encoded protein in rodents has been shown to bind PDGFA with a low affinity. PDGF-Associated Protein (PAP) is a phosphoprotein that may enhance PDGFA-stimulated cell growth in fibroblasts, but inhibits the mitogenic effect of PDGFB. PDAP1 expression is induced by TNF-alpha, and cells overexpressing PDAP1 show significantly less apoptosis on exposure to TNF-alpha.

• NCBI Gene ID:

  11333

• Swiss Prot:

  Q13442

• Accession Number:

  Q13442

• Tag:

  N-6 His tag

• Type:

  Recombinant Proteins

• Source:

  E. coli

• Field of Research:

  Signal Transduction

• Buffer:

  Supplied as a 0.2 um filtered solution of 20mM Tris, 100mM NaCl, 0.1mM PMSF, 2mM DTT, pH 8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.

• Shipping Conditions:

  Dry Ice

• Calculated Molecular Weight:

  22.79 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  PDGFA associated protein 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  28 kDa Heat- and Acid-Stable Phosphoprotein, PDGF-Associated Protein, PAP, PDGFA-Associated Protein 1, PAP1, PDAP1, HASPP28

• Species:

  Human

• Protein ID:

  767904139

• Physical Properties:

  Liquid

• CAS Number:

  9000-83-3