CCL8 Recombinant Protein

• Background:

  Human Chemokine (C-C Motif) Ligand 8 (CCL8) is produced by human MG63 osteosarcoma cells. CCL8 shares 62% and 58% amino acid sequence identity with MCP-1 and MCP-3, respectively. All three MCP proteins are monocyte chemoattractants. CCL8 is chemotactic for and activates many different immune cells, including mast cells, eosinophils and basophils, which are implicated in allergic response, and monocytes, T cells, and NK cells that are involved in the inflammatory response. CCL8 elicits its effects by binding to several different cell surface receptors including CCR1, CCR2B and CCR5.

• NCBI Gene ID:

  6355

• Swiss Prot:

  P80075

• Accession Number:

  P80075

• Tag:

  C-6 His tag

• Type:

  Recombinant Proteins

• Source:

  Human Cells

• Field of Research:

  Chemokines & Cytokines

• Buffer:

  Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl,1mM EDTA, pH 7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

• Shipping Conditions:

  Room Temp

• Calculated Molecular Weight:

  9.95 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  C-C motif chemokine ligand 8

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  C-C Motif Chemokine 8, HC14, Monocyte Chemoattractant Protein 2, Monocyte Chemotactic Protein 2, MCP-2, Small-Inducible Cytokine A8, CCL8, MCP2, SCYA10, SCYA8

• Species:

  Human

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3