Fructose-1,6-Bisphosphatase 1 Recombinant Protein

• Background:

  Fructose-1,6-bisphosphatase 1 (FBP1) is a homotetramer protein and belongs to the FBPase class 1 family. It involves in carbohydrate biosynthesis; gluconeogenesis pathway. FBP1 is a gluconeogenesis regulatory protein which catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. FBP1 deficiency is associated with hypoglycemia and metabolic acidosis. FBP1 regulates mouse endogenous glucose production. FBP1 coupled with phosphofructokinase (PFK) takes part in the metabolism of pancreatic islet cells.

• NCBI Gene ID:

  2203

• Swiss Prot:

  P09467

• Accession Number:

  P09467

• Tag:

  C-6 His tag

• Type:

  Recombinant Proteins

• Source:

  Human Cells

• Field of Research:

  Cancer, Obesity, Signal Transduction

• Buffer:

  Supplied as a 0.2 um filtered solution of 20mM TrisHCl,200mM NaCl,1mM DTT,10% Glycerol, pH 8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.

• Shipping Conditions:

  Dry Ice

• Calculated Molecular Weight:

  37.8 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Fructose-bisphosphatase 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Fructose-1, 6-bisphosphatase 1, D-fructose-1, 6-bisphosphate 1-phosphohydrolase 1, FBP, FBPase 1

• Species:

  Human

• Physical Properties:

  Liquid

• CAS Number:

  9000-83-3