Fructose-1,6-Bisphosphatase 1 Recombinant Protein

• Background:

  Fructose-1,6-Bisphosphatase 1 (FBPase 1) is a member of the FBPase class 1 family. FBPase 1 is a gluconeogenesis regulatory protein, which catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. FBPase 1 can assume an active R-state, or an inactive T-state. FBPase 1 deficiency is inherited as an autosomal recessive disorder mainly in the liver and causes life-threatening episodes of hypoglycemia and metabolic acidosis in newborn infants or young children. FBPase 1 coupled with phosphofructokinase (PFK) is involved in the metabolism of pancreatic islet cells.

• NCBI Gene ID:

  2203

• Swiss Prot:

  P09467

• Accession Number:

  P09467

• Tag:

  C-6 His tag

• Type:

  Recombinant Proteins

• Source:

  E. coli

• Field of Research:

  Cancer, Obesity, Signal Transduction

• Buffer:

  Supplied as a 0.2 um filtered solution of 20mM TrisHCl, 200mM NaCl, 1mM DTT, 1mM EDTA, 20% Glycerol, pH 8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.

• Shipping Conditions:

  Dry Ice

• Calculated Molecular Weight:

  37.89 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Fructose-bisphosphatase 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Fructose-1, 6-Bisphosphatase 1, FBPase 1, D-Fructose-1, 6-Bisphosphate 1-Phosphohydrolase 1, FBP1, FBP

• Species:

  Human

• Physical Properties:

  Liquid

• CAS Number:

  9000-83-3