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FGF-2 Recombinant Protein

CAT: 0223-90-331Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0223-90-331Size:10 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
FGF-2 (Basic fibroblast growth factor) belongs to the FGF superfamily that is made up of 22 different fibroblast growth factor genes. FGF-2 and FGF-1 (acidic FGF) are unique in that they do not follow the conventional signal sequence for secretion. FGF-2 is found in five isoforms via alternative initiation of translation. Signaling of FGF-2 occurs through the high-affinity tyrosine kinase receptors FGFR1-4. FGF-2 is a potent wide-spectrum mitogen whose overexpression is associated with immortalization and unregulated cell proliferation in many tumors. FGF-2 functions in angiogenesis, cell survival, tissue repair, embryonic development and inflammation. FGF-2 is widely used to maintain the self-renewal of human embryonic stem cells (ESCs) and to induce pluripotent stem cells. FGF-2 is an established neurogenic factor for proliferation and differentiation of multipotent neural stem cells both during development and in the adult mouse brain as well.
CAS Number
9000-83-3
NCBI Gene ID
2247
Swiss Prot
P12643
Accession Number
P09038
Tag
Tag Free
Type
Recombinant Proteins
Source
E. coli
Field of Research
Growth Factors
Concentration
0.1mg/ml after reconstitution.
Buffer
Contains PBS + 0.1mM DTT. Reconstitute with 100 μ l sterile water.
Shipping Conditions
Room Temp
Storage Conditions
Stable for at least 6 months after receipt when stored at -20˚ C.
Applications Notes
This recombinant proteins is for research use only.
NCBI Official Name
Fibroblast growth factor 2 (basic)
NCBI Organism
Homo sapiens
Other Product Names
Basic Fibroblast Growth Factor, bFGF, Heparin Binding Growth Factor-2, HBGF-2
Species
Human
Protein ID
261260095
Physical Properties
Lyophilized

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