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TYRO3 Recombinant Protein

CAT: 0223-92-447Size: 0.05 mgDry Ice: NoHazardous: No
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CAT#:0223-92-447Size:0.05 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Dtk, also called Tyro3, belongs to the TAM receptor family of receptor protein tyrosine kinases (RPTKs) composed of three receptors Tyro3, Axl, and Mer. These receptors share a characteristic molecular structure of two immunoglobulin-like and two fibronectin type III repeats and have been best characterized for their roles in immune regulation, fertility, thrombosis and phagocytosis. Gas6 and protein S have been identified as ligands for these receptors. Gas6 binding induces tyrosine phosphorylation and downstream signaling pathways that can lead to cell proliferation, migration, or the prevention of apoptosis. Tyro3 and Axl play important regulatory roles in a variety of tissues, including the central nervous, reproductive, immune, and vascular systems. Tyro3 is widely expressed during embryonic development and preferentially expressed during neurogenesis in the central nervous system.
CAS Number
9000-83-3
NCBI Gene ID
22174
Swiss Prot
P55144
Accession Number
P55144
Tag
C-mFc tag
Type
Recombinant Proteins
Source
Human Cells
Buffer
Lyophilized from a 0.2 um filtered solution of PBS, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Calculated Molecular Weight
68.2 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
TYRO3 protein tyrosine kinase 3
NCBI Organism
Mus musculus
Other Product Names
Tyrosine-protein kinase receptor TYRO3, Tyro3, Etk2/tyro3, TK19-2, Tyrosine-protein kinase DTK, Tyrosine-protein kinase RSE, Tyrosine-protein kinase TIF, Dtk
Species
Mouse
Physical Properties
Lyophilized

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