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ADAM8 Recombinant Protein

CAT: 0223-96-013Size: 0.05 mgDry Ice: NoHazardous: No
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CAT#:0223-96-013Size:0.05 mg
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Background
Disintegrin and metalloproteinase domain-containing protein 8 is also known as ADAM8, Cell surface antigen MS2 and CD antigen CD156a, which belongs to the ADAM (a disintegrin and metalloprotease domain) family. ADAM family play a fundamental role in diverse processes such as asthma, development, angiogenesis and cancer through their activities in cell adhesion/fusion, membrane protein shedding, and signal transduction. ADAM8 / CD156a contains 1 disintegrin domain, 1 EGF-like domain and 1 peptidase M12B domain. ADAM8 / MS2 / CD156a is expressed on neutrophils and monocytes. ADAM8 / MS2 possible involvement in extravasation of leukocytes.
CAS Number
9000-83-3
NCBI Gene ID
101
Swiss Prot
P78325
Accession Number
AAI15405.1
Tag
His Tag
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Cancer, Cell Cycle, Homeostasis, Signal Transduction, Other
Purity
>85% as determined by SDS-PAGE.
Buffer
50 mM Tris, 150 mM NaCl, 20 mM CaCl2, pH7.5
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
71.6 kDa
Applications Notes
This recombinant protein can be used for WB. For research use only.
NCBI Official Name
ADAM metallopeptidase domain 8
NCBI Organism
Homo sapiens
Background Reference 01
Yoshiyama K., et al., 1997, Genomics 41 : 56–62.
Background Reference 02
Hall T., et al., 2012, Acta Crystallogr. F 68:616-621.
Other Product Names
ADAM8, MS2, CD156a
Tested Applications
WB
Species
Human
Physical Properties
Lyophilized

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