ADAM8 Recombinant Protein

• Background:

  Disintegrin and metalloproteinase domain-containing protein 8 is also known as ADAM8, Cell surface antigen MS2 and CD antigen CD156a, which belongs to the ADAM (a disintegrin and metalloprotease domain) family. ADAM family play a fundamental role in diverse processes such as asthma, development, angiogenesis and cancer through their activities in cell adhesion/fusion, membrane protein shedding, and signal transduction. ADAM8 / CD156a contains 1 disintegrin domain, 1 EGF-like domain and 1 peptidase M12B domain. ADAM8 / MS2 / CD156a is expressed on neutrophils and monocytes. ADAM8 / MS2 possible involvement in extravasation of leukocytes.

• NCBI Gene ID:

  101

• Swiss Prot:

  P78325

• Accession Number:

  AAI15405.1

• Tag:

  His Tag

• Type:

  Recombinant Proteins

• Source:

  HEK293 cells

• Field of Research:

  Cancer, Cell Cycle, Homeostasis, Signal Transduction, Other

• Purity:

  >85% as determined by SDS-PAGE.

• Buffer:

  50 mM Tris, 150 mM NaCl, 20 mM CaCl2, pH7.5

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.

• Calculated Molecular Weight:

  71.6 kDa

• Applications Notes:

  This recombinant protein can be used for WB. For research use only.

• NCBI Official Name:

  ADAM metallopeptidase domain 8

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Yoshiyama K., et al., 1997, Genomics 41 : 56–62.

• Background Reference 02:

  Hall T., et al., 2012, Acta Crystallogr. F 68:616-621.

• Other Product Names:

  ADAM8, MS2, CD156a

• Tested Applications:

  WB

• Species:

  Human

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3