Dipeptidase 1 Recombinant Protein

• Background:

  Dipeptidase 1 (DPEP1) is a kidney membrane enzyme that belongs to the peptidase M19 family. DPEP1 is a homodimer and is inhibited by L-penicillamine. DPEP1 hydrolyzes a variety of dipeptides and is implicated in renal metabolism of glutathione and its conjugates. DPEP1 is responsible for hydrolysis of the beta-lactam ring of antibiotics, such as penem and carbapenem. DPEP1 may play an important role in the regulation of leukotriene activity. DPEP1 expression in cancer is significantly higher than that in normal tissue. However, DPEP1 expression decreased with pathological differentiation, lymph-node and distant metastasis.

• NCBI Gene ID:

  1800

• Swiss Prot:

  P16444

• Accession Number:

  P16444

• Tag:

  C-6 His tag

• Type:

  Recombinant Proteins

• Source:

  Human Cells

• Field of Research:

  Other

• Buffer:

  Supplied as 0.2 um filtered solution of 20mM PBS, 10% Glycerol , pH7.4.

• Shipping Conditions:

  Blue Ice

• Calculated Molecular Weight:

  42.1 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Dipeptidase 1 (renal)

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Dipeptidase 1, Dehydropeptidase-I, Microsomal Dipeptidase, Renal Dipeptidase, hRDP, DPEP1, MDP, RDP

• Species:

  Human

• Physical Properties:

  Liquid

• CAS Number:

  9000-83-3