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CRADD Recombinant Protein

CAT: 0223-92-117Size: 0.05 mgDry Ice: NoHazardous: No
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CAT#:0223-92-117Size:0.05 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Death Domain-Containing Protein CRADD (CRADD) is widely expressed in most tissues, with particularly high expression in the adult heart, testis, liver, skeletal muscle, fetal liver, and kidney. CRADD contains one CARD domain that mediates the interaction with caspase-2, and one death domain involved in the binding of RIP protein. CRADD functions as an apoptotic adaptor molecule specific for caspase-2 and FASL/TNF receptor-interacting protein RIP. CRADD induces cell apoptosis/cell death in numerous tissues. Defects in CRADD will result in mental retardation.
CAS Number
9000-83-3
NCBI Gene ID
8738
Swiss Prot
P78560
Accession Number
P78560
Tag
Tag Free
Type
Recombinant Proteins
Source
E. coli
Field of Research
Apoptosis, Cancer, Other
Buffer
Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Calculated Molecular Weight
23 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
CASP2 and RIPK1 domain containing adaptor with death domain
NCBI Organism
Homo sapiens
Other Product Names
Death Domain-Containing Protein CRADD, Caspase and RIP Adapter with Death Domain, RIP-Associated Protein with A Death Domain, CRADD, RAIDD
Species
Human
Physical Properties
Lyophilized

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