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CD94 Recombinant Protein

CAT: 0223-11-330Size: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0223-11-330Size:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CD94 (Natural killer cells antigen CD94) is also known as KLRD1, KP43, NK cell receptor, Killer cell lectin-like receptor subfamily D member 1. CD94 plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. CD94 pairs with the NKG2 molecule as a heterodimer. The CD94/NKG2 complex, on the surface of natural killer cells interacts with Human Leukocyte Antigen (HLA) -E on target cells.
CAS Number
9000-83-3
Tag
His Tag
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Signal Transduction, Stem Cell, Other
Purity
>90% as determined by SDS-PAGE.
Buffer
PBS, pH7.4
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
19.1 kDa
Applications Notes
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 19.1 kDa. The protein migrates as 24-30 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Background Reference 01
Petrie EJ. J Exp Med. 2008. 205 (3) :725-35.
Background Reference 02
Kaiser BK. Proc Natl Acad Sci U S A. 2008. 105 (18) :6696-701.
Background Reference 03
Sullivan LC. Immunity. 2007. 27 (6) :900-11.
Other Product Names
CD94, KLRD1, KP43, NK cell receptor
Tested Applications
WB
Species
Human
Physical Properties
Lyophilized

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