CD99 Recombinant Protein

• Background:

  CD99 antigen is also known as MIC2, single-chain type-1 glycoprotein, HBA71, MIC2X, MIC2Y, MSK5X, 12E7, which belongs to the CD99 family. CD99 / MIC2 is expressed on all leukocytes but highest on thymocytes. Involved in T-cell adhesion processes and in spontaneous rosette formation with erythrocytes. CD99 / MIC2 plays a role in a late step of leukocyte extravasation helping leukocytes to overcome the endothelial basement membrane. CD99 acts at the same site as, but independently of PECAM1. There is also experimental evidence that it binds to cyclophilin A.

• NCBI Gene ID:

  4267

• Swiss Prot:

  P14209

• Accession Number:

  AAH02584

• Tag:

  C-Fc Tag

• Type:

  Recombinant Proteins

• Source:

  HEK293 cells

• Field of Research:

  Signal Transduction

• Purity:

  >92% as determined by SDS-PAGE.

• Buffer:

  50 mM tris, 100 mM glycine, pH7.5

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.

• Calculated Molecular Weight:

  36.2 kDa

• Applications Notes:

  This recombinant protein can be used for WB. For research use only.

• NCBI Official Name:

  CD99 molecule

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Gelin C., et al., 1989, EMBO J. 8:3253-3259.

• Background Reference 02:

  Aussel C., et al., 1993, Biochemistry 32 (38) : 10096–101.

• Background Reference 03:

  Dworzak MN., et al., 1994, Blood 83 (2) : 415–25.

• Background Reference 04:

  Bernard G., et al., 1997, Journal of immunology (Baltimore, Md. : 1950) 158 (6) : 2543–50.

• Other Product Names:

  CD99, HBA71, MIC2, MIC2X, MIC2Y, MSK5X, 12E7

• Tested Applications:

  WB

• Species:

  Human

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3