CD94 Antibody [18d3]

• Background:

  The monoclonal antibody 18d3 reacts with the mouse CD94 receptor subunit, a type II transmembrane glycoprotein. CD94 is expressed on the surface of NK cells, NK T cells, and some memory phenotype CD8+ cells. When CD94 is paired with NKG2A, C, or E subunit, it binds the nonclassical MHC class Ib molecule Qa-1b and results in a CD94high population by flow cytometry. Approximately half of NK cells do not express NKG2A, C or E; these cells express CD94 on the surface in a form that does not bind Qa-1b and is believed to be nonfunctional, producing a CD94low population by flow cytometry. CD94 is thought to play a role in the adhesion and activation of the NK cell lineage.

• NCBI Gene ID:

  16643

• Swiss Prot:

  O54707

• Accession Number:

  O54707

• Host:

  Rat

• Reactivity:

  Mouse

• Immunogen:

  CHO cells transfected with the B6 allele of CD94

• Clonality:

  Monoclonal

• Clone:

  [18d3]

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Immunology

• Concentration:

  0.5 mg/mL

• Buffer:

  Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store vial at 2-8˚ C

• Fragment:

  IgG2a

• Specificity:

  CD94

• Applications Notes:

  CD94 Antibody [18d3] for use in flow cytometry assays.

• Symbol:

  Klrd1

• NCBI Official Name:

  Killer cell lectin-like receptor, subfamily D, member 1

• NCBI Organism:

  Mus musculus

• Other Product Names:

  Kp43, KLRD1

• Tested Applications:

  ELISA, IHC-Fr, Flow, IP

• Physical Properties:

  Liquid