C1qTNF1 Recombinant Protein

• Background:

  C1QTNF1 is a secreted protein, contains 1 C1q domain and 1 collagen-like domain. C1qTNF proteins constitute a highly conserved family of Acrp30/Adiponectin paralogs that share a modular organization comprising an N-terminal signal peptide, a short variable region, a collagenous domain and a C-terminal globular domain. C1qTNF proteins are predicted to have trimeric structures that assemble into hexameric and higher order molecular forms. C1QTNF1 is a novel adipokine, providing a significant framework to further address the physiological functions and mechanisms of the action of this family of secreted glycoproteins in normal and disease states. C1QTNF1 increases the production of aldosterone. C1QTNF1 is vastly expressed in obese subjects as well as up-regulated in hypertensive patients, C1QTNF1 is identified molecular link between obesity and hypertension. C1QTNF1 expression may be associated with a low-grade chronic inflammation status in adipose tissues.

• NCBI Gene ID:

  114897

• Swiss Prot:

  Q9BXJ1

• Accession Number:

  Q9BXJ1

• Tag:

  C-6 His tag

• Type:

  Recombinant Proteins

• Source:

  Human Cells

• Field of Research:

  Immunology, Obesity, Signal Transduction

• Buffer:

  Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

• Shipping Conditions:

  Room Temp

• Calculated Molecular Weight:

  30.24 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  C1q and tumor necrosis factor related protein 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Complement C1q Tumor Necrosis Factor-Related Protein 1, G Protein-Coupled Receptor-Interacting Protein, GIP, C1QTNF1, CTRP1

• Species:

  Human

• Protein ID:

  767932354

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3