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BTNL2 Recombinant Protein

CAT: 0223-90-375Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0223-90-375Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Butyrophilin-like 2 (BTNL2) is a butyrophilin family member with homology to the B7 costimulatory molecules, polymorphisms of which have been recently associated through genetic analysis; to sporadic inclusion body myositis and sarcoidosis. BTNL2 mRNA is highly expressed in lymphoid tissues as well as in intestine. BTNL2-Ig fusion protein was shown to recognize a putative receptor whose expression on B and T cells was significantly enhanced after activation. It inhibited T cell proliferation and TCR activation of NFAT, NF-kappaB and AP-1 signaling pathways. BTNL2 is the first member of the butyrophilin family that regulates T cell activation, which has implications in immune diseases and immunotherapy.
CAS Number
9000-83-3
NCBI Gene ID
547431
Swiss Prot
O95971
Accession Number
NP_524574
Tag
Fc Tag
Type
Recombinant Proteins
Source
CHO cells
Buffer
Lyophilized from 0.2um-filtered solution in PBS. Reconstitute at 100 μ g/ml in sterile PBS.
Shipping Conditions
Room Temp
Storage Conditions
Stable for at least 1 year after receipt when stored at -20˚ C. Working aliquots are stable for up to 3 months when stored at -20˚ C.
Applications Notes
This recombinant proteins is for research use only.
NCBI Official Name
Butyrophilin-like 2
NCBI Organism
Mus musculus
Other Product Names
Butyrophilin-like Protein 2
Species
Mouse
Protein ID
83721945
Physical Properties
Lyophilized

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