CD72 Recombinant Protein

• Background:

  B-Cell Differentiation Antigen CD72 (CD72) is a single-pass type II membrane protein. CD72 exists as a disulfide-linked homodimer and contains one C-type lectin domain. CD72 is expressed on B lineage cells, NK cells, monocytes, dendritic cells, and mast cells. CD72 is a ligand for CD5. CD72 associates with CD5, interacts with PTPN6/SHP-1 and plays a role in B-cell proliferation and differentiation. CD72 associates with CD79A in the B cell antigen receptor (BCR) complex following antigen stimulation and dampens BCR signaling through interactions with the phosphatase SHP-1.

• NCBI Gene ID:

  971

• Swiss Prot:

  P21854

• Accession Number:

  P21854

• Tag:

  N-Trx, 6 His tag

• Type:

  Recombinant Proteins

• Source:

  E. coli

• Field of Research:

  Immunology, Signal Transduction

• Buffer:

  Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

• Shipping Conditions:

  Room Temp

• Calculated Molecular Weight:

  30.6 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  CD72 molecule

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  B-Cell Differentiation Antigen CD72, Lyb-2, CD72, Lyb‑2

• Species:

  Human

• Protein ID:

  578877726

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3