CD72.1 Antibody [10.1.D2] (FITC)

• Background:

  Murine CD72.1 (Lyb-2.1), a type II integral membrane glycoprotein and a member of the C-lectin family of cell surface receptors, is a differentiation antigen of B cells and is found in mouse strains expressing the Lyb-2.1 allotype. CD72.1 is the ligand of CD5 which is distributed on all T cells and a small number of B cells. The 10.1.D2 monoclonal antibody blocks binding of CD5 to CD72 on the B cell surface which leads to inhibition of the positive signal resulting from CD5/CD72 pairing. However, 10.1.D2 can itself trigger a positive signal by binding CD72.

• NCBI Gene ID:

  12517

• Swiss Prot:

  P21855

• Accession Number:

  P21855

• Host:

  Mouse

• Reactivity:

  Mouse

• Immunogen:

  DBA/2 mouse spleen cells

• Clonality:

  Monoclonal

• Clone:

  [10.1.D2]

• Conjugation:

  FITC

• Type:

  Primary Antibodies

• Field of Research:

  Immunology, Signal Transduction

• Concentration:

  0.5 mg/mL

• Buffer:

  Supplied in PBS/NaN3

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store vial at 2-8˚ C

• Fragment:

  IgG2b

• Specificity:

  CD72.1

• Applications Notes:

  CD72.1 Antibody [10.1.D2] for use in flow cytometry assays.

• Symbol:

  Cd72

• NCBI Official Name:

  CD72 antigen

• NCBI Organism:

  Mus musculus

• Other Product Names:

  Lyb-2.1, CD72a, Lyb-2a

• Tested Applications:

  WB, IHC-Fr, ICC, Flow, Blocking, IP

• Physical Properties:

  Liquid