Bcl-2-associated Athanogene 1 Recombinant Protein

• Background:

  BAG Family Molecular Chaperone Regulator 2 (BAG2) is a member of the Bag family whose members compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. BAG2 contains 1 BAG domain and is a important component of the HSC 70/CHIP chaperone-dependent ubiquitin ligase complex. In mammalian cells BAG1, BAG2, and BAG3 bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.

• NCBI Gene ID:

  9532

• Swiss Prot:

  O95816

• Accession Number:

  O95816

• Tag:

  N-6 His tag

• Type:

  Recombinant Proteins

• Source:

  E. coli

• Field of Research:

  Cancer, Cell Cycle, Obesity, Signal Transduction

• Buffer:

  Lyophilized from a 0.2 um filtered solution of 20mM TrisHCl, 150mM NaCl, pH 8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

• Shipping Conditions:

  Room Temp

• Calculated Molecular Weight:

  25.9 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  BCL2 associated athanogene 2

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  BAG Family Molecular Chaperone Regulator 2, BAG-2, Bcl-2-Associated Athanogene 2, BAG2

• Species:

  Human

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3