BIRC5 Recombinant Protein

• Background:

  Baculoviral IAP Repeat-Containing Protein 5 (BIRC5) belongs to the IAP family. BIRC5 exists as a homodimer in the apo state and as a monomer in the CPC-bound state. BIRC5 contains one BIR repeat and is expressed only in fetal kidney and liver, and to lesser extent, lung and brain. BIRC5 functions as a multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis. BIRC5 is also a component of a chromosome passage protein complex (CPC), which is essential for chromosome alignment and segregation during mitosis and cytokinesis. BIRC5 acts as an important regulator of the localization of this complex.

• NCBI Gene ID:

  332

• Swiss Prot:

  O15392

• Accession Number:

  O15392

• Tag:

  Tag Free

• Type:

  Recombinant Proteins

• Source:

  E. coli

• Field of Research:

  Apoptosis, Cancer, Growth Factors, Neuroscience

• Buffer:

  Lyophilized from a 0.2 um filtered solution of 20mM Tris, 0.1M NaCl, pH 7.5. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

• Shipping Conditions:

  Room Temp

• Calculated Molecular Weight:

  20.4 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Baculoviral IAP repeat containing 5

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Baculoviral IAP Repeat-Containing Protein 5, Apoptosis Inhibitor 4, Apoptosis Inhibitor Survivin, BIRC5, API4, IAP4

• Species:

  Human

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3