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B18R Recombinant Protein

CAT: 0223-92-624Size: 0.05 mgDry Ice: NoHazardous: No
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CAT#:0223-92-624Size:0.05 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
B18R, also known as B19R in the Copenhagen strain of Vaccinia, is a type I interferon (IFN) -binding protein encoded by the B18R open reading frame in the Western Reserve strain of vaccinia virus. B18R exists in two forms, soluble and membrane-bound form and also has a broad species specificity. B18R has high affinity for human IFN-alpha and also binds rabbit, bovine, rat, pig, and mouse IFN-alpha and IFN-beta. Secreted B18R binds to uninfected and infected cells. B18R presents at the cell surface and protects cells from the antiviral state. It has shown that binding of soluble recombinant B18R protects cultured cells from IFN and allows vaccinia virus replication.
CAS Number
9000-83-3
NCBI Gene ID
3707577
Swiss Prot
P25213
Accession Number
P25213
Tag
C-6 His tag
Type
Recombinant Proteins
Source
Human Cells
Buffer
Lyophilized from a 0.2 um filtered solution of PBS, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Calculated Molecular Weight
39.2 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Temporal expression: early
NCBI Organism
Vaccinia virus
Other Product Names
Soluble interferon alpha/beta receptor B18, VACWR200
Species
Vacciniavirus
Physical Properties
Lyophilized

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