Rhesus Macaque ACE-2 Recombinant Protein

• Background:

  Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor don’t inhibit ACE-2 activity. ACE-2 may play an important role in regulating the heart function.

• NCBI Gene ID:

  712790

• Swiss Prot:

  ACI04564.1

• Accession Number:

  ACI04564.1

• Tag:

  C-Fc tag

• Type:

  Recombinant Proteins

• Source:

  Mammalian Cells

• Field of Research:

  Infectious Disease

• Buffer:

  Supplied as a 0.2 um filtered solution of PBS, pH 7.4.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store below -20˚ C, stable for 6 months after receipt.

• Calculated Molecular Weight:

  110.6kDa

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Angiotensin-converting enzyme 2

• NCBI Organism:

  Macaca mulatta

• Other Product Names:

  Angiotensin-Converting Enzyme 2; ACE-Related Carboxypeptidase; Angiotensin-Converting Enzyme Homolog; ACEH; Metalloprotease MPROT15; ACE2

• Species:

  Rhesus monkey

• Physical Properties:

  Liquid

• CAS Number:

  9000-83-3