Aldehyde dehydrogenase 1-A2 Recombinant Protein

• Background:

  Aldehyde dehydrogenase 1 family member A2 (ALDH1A2), also known as retinaldehyde dehydrogenase 2 (RALDH2), belongs to the aldehyde dehydrogenase family which contains two members, the ALDH1 s (ALDH1A1, ALDH1A2 and ALDH1A3) and the 9-cis retinaldehyde dehydrogenase ALDH8 s. ALDH1A2 is key enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. RA is a paracrine hormone signaling molecule that functions in developing and adult tissues. ALDH1A2 was also found to regulate normal and tumor cell growth and differentiation. Several studies showed that ALDH1A2 expression is increased after the appearance of AraC resistance in clinical cases which means this protein is effective in AraC resistance.

• NCBI Gene ID:

  8854

• Swiss Prot:

  O94788

• Accession Number:

  O94788

• Tag:

  N-6 His tag

• Type:

  Recombinant Proteins

• Source:

  E. coli

• Buffer:

  Supplied as a 0.2 um filtered solution of 20mM TrisHCl,150mMNaCl, pH7.5,20% Glycerol. It is not recommended to reconstitute to a concentration less than 100 ug/ml.

• Shipping Conditions:

  Dry Ice

• Calculated Molecular Weight:

  58.2 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Aldehyde dehydrogenase 1 family member A2

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Aldehyde dehydrogenase family 1 member A2, Retinaldehyde-specific dehydrogenase type 2, RALDH (II), Retinal dehydrogenase 2, ALDH1A2, RALDH2

• Species:

  Human

• Physical Properties:

  Liquid

• CAS Number:

  9000-83-3