Cyclin A2 Antibody [E67]

CAT: 0223-33-074Size: 100 µgDry Ice: NoHazardous: No
CAT#:0223-33-074Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This antibody recognizes a protein of 50-55 kDa, which is identified as Cyclin A. Its epitope is located amino acids 144-148 of the human protein. Cyclins are regulatory subunits of the cyclin-dependent kinases (cdk’s) and they control transition at different specific phases of the cell cycle. The temporal expression of cyclins is tightly regulated and subsequently plays a critical role in controlling the enzymatic activity of cdk’s. These cyclin/cdk complexes are essential for passage through specific stages in the cell cycle. In mammalian somatic cells, Cyclin A is required for S-phase and passage through G2-phase. The D and E type cyclins regulate the passage of G1, while Cyclin B is a critical regulator of mitosis. Mutation or disruption of normal Cyclin A expression causes cells to arrest in G2-phase.
NCBI Gene ID
890
Swiss Prot
P20248
Host
Mouse
Reactivity
Human, Mouse, Bovine, African Green Monkey, Mink
Immunogen
Full length bovine protein was used as the immunogen for this CCNA2 antibody.
Clonality
Monoclonal
Clone
E67
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle
Purification
Protein G affinity chromatography
Concentration
0.2 mg/mL
Buffer
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.
Fragment
IgG2a, kappa
Symbol
CCNA2
NCBI Official Name
Cyclin A2
NCBI Organism
Homo sapiens
Other Product Names
Cyclin-A2, Cyclin-A, CCNA2, CCN1, CCNA
Tested Applications
WB, Flow, IF
Physical Properties
Liquid

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