Cyclin A2 Antibody [E67]

• Background:

  This antibody recognizes a protein of 50-55 kDa, which is identified as Cyclin A. Its epitope is located amino acids 144-148 of the human protein. Cyclins are regulatory subunits of the cyclin-dependent kinases (cdk’s) and they control transition at different specific phases of the cell cycle. The temporal expression of cyclins is tightly regulated and subsequently plays a critical role in controlling the enzymatic activity of cdk’s. These cyclin/cdk complexes are essential for passage through specific stages in the cell cycle. In mammalian somatic cells, Cyclin A is required for S-phase and passage through G2-phase. The D and E type cyclins regulate the passage of G1, while Cyclin B is a critical regulator of mitosis. Mutation or disruption of normal Cyclin A expression causes cells to arrest in G2-phase.

• NCBI Gene ID:

  890

• Swiss Prot:

  P20248

• Host:

  Mouse

• Reactivity:

  Human, Mouse, Bovine, African Green Monkey, Mink

• Immunogen:

  Full length bovine protein was used as the immunogen for this CCNA2 antibody.

• Clonality:

  Monoclonal

• Clone:

  E67

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle

• Purification:

  Protein G affinity chromatography

• Concentration:

  0.2 mg/mL

• Buffer:

  PBS with 0.1 mg/ml BSA and 0.05% sodium azide

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.

• Fragment:

  IgG2a, kappa

• Symbol:

  CCNA2

• NCBI Official Name:

  Cyclin A2

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Cyclin-A2, Cyclin-A, CCNA2, CCN1, CCNA

• Tested Applications:

  WB, Flow, IF

• Physical Properties:

  Liquid