Aldehyde Dehydrogenase 1-A1 Recombinant Protein

• Background:

  Aldehyde Dehydrogenase Family 1 Member A1 (ALDH1A1) is a cytoplasmic enzyme that belongs to the Aldehyde Dehydrogenase family. ALDH1A1 is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties and subcellular localizations. ALDH1A1 is the main cytosolic isoform, which has a lower affinity for aldehydes than the mitochondrial enzyme. ALDH1A1 binds free retinal and cellular retinol-binding protein-bound retinal. It can convert/oxidize retinaldehyde to retinoic acid.

• NCBI Gene ID:

  216

• Swiss Prot:

  P00352

• Accession Number:

  P00352

• Tag:

  N-6 His tag

• Type:

  Recombinant Proteins

• Source:

  E. coli

• Field of Research:

  Cancer, Neuroscience, Signal Transduction

• Buffer:

  Supplied as a 0.2 um filtered solution of 20mM TrisHCl, pH8.5. It is not recommended to reconstitute to a concentration less than 100 ug/ml.

• Shipping Conditions:

  Dry Ice

• Calculated Molecular Weight:

  57 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Aldehyde dehydrogenase 1 family member A1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Retinal Dehydrogenase 1, RALDH 1, RalDH1, ALDH-E1, ALHDII, Aldehyde Dehydrogenase Family 1 Member A1, Aldehyde Dehydrogenase Cytosolic, ALDH1A1, ALDC, ALDH1, PUMB1

• Species:

  Human

• Physical Properties:

  Liquid

• CAS Number:

  9000-83-3