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Adiponectin Recombinant Protein

CAT: 0223-91-501Size: 0.05 mgDry Ice: NoHazardous: No
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CAT#:0223-91-501Size:0.05 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Adiponectin is a secreted protein. It is synthesized exclusively by adipocytes and secreted into plasma. Adiponectin is an important adipokine that is involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Adiponectin Stimulates AMPK phosphorylation and activates in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Adiponectin also antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. It inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. Adiponectin may play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex: LMW, MMW or HMW.
CAS Number
9000-83-3
NCBI Gene ID
9370
Swiss Prot
Q15848
Accession Number
Q15848
Tag
C-6 His tag
Type
Recombinant Proteins
Source
Human Cells
Field of Research
Neuroscience, Obesity, Signal Transduction, Stem Cell
Buffer
Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Calculated Molecular Weight
25.58 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Adiponectin, C1Q and collagen domain containing
NCBI Organism
Homo sapiens
Other Product Names
Adiponectin, 30 kDa Adipocyte Complement-Related Protein, Adipocyte complement-related 30 kDa protein, ACRP30, Adipocyte, C1q and Collagen Domain-Containing Protein, Adipose Most Abundant Gene Transcript 1 Protein, apM-1, Gelatin-Binding Protein, ADIPOQ, ACDC, APM1, GBP28
Species
Human
Protein ID
767928039
Physical Properties
Lyophilized

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