PDE5-IN-7

PDE5-IN-7

• CAS Number: 139756-21-1
• UNSPSC Description: PDE5-IN-7 (compound 8) is a selective phosphodiesterase 5 (PDE 5) inhibitor with an IC50 value of 5 nM, while an IC50 of 300 nM for PDE 1[1].
• Target Antigen: Phosphodiesterase (PDE)
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Metabolism-protein/nucleotide metabolism
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/pde5-in-7.html
• Purity: 99.83
• Solubility: DMSO : 33.33 mg/mL (ultrasonic)
• Smiles: O=C1C(N(C)N=C2CCC)=C2N=C(C3=CC=CC=C3OCC)N1
• Molecular Weight: 312.373
• References & Citations: [1]Haning H, et al. Imidazo[5,1-f]triazin-4(3H)-ones, a new class of potent PDE 5 inhibitors. Bioorg Med Chem Lett. 2002 Mar 25;12(6):865-8. |[2]Assemat G, et al. Isolation and identification of ten new sildenafil derivatives in an alleged herbal supplement for sexual enhancement. J Pharm Biomed Anal. 2020 Nov 30;191:113482.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported