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Phensuximide (Standard)

CAT: 0804-HY-B1730R-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B1730R-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Phensuximide (Standard) is the analytical standard of Phensuximide. This product is intended for research and analytical applications. Phensuximide is an orally active succinimide antiepileptic and anticonvulsant agent. Phensuximide inhibits cyclic AMP and cyclic GMP accumulation in depolarized brain tissue. Phensuximide can be used for the study of seizure and petit mal[1][3].
CAS Number
86-34-0
UNSPSC
12352005
Target
Cyclic GMP-AMP Synthase; Reference Standards
Type
Reference compound
Related Pathways
Immunology/Inflammation; Others
Field of Research
Metabolic Disease; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/phensuximide-standard.html
Smiles
O=C(C(C1=CC=CC=C1)C2)N(C)C2=O
Molecular Formula
C11H11NO2
Molecular Weight
189.21
References & Citations
[1]G O Rankin, et al. Urinary Tract Effects of Phensuximide in the Sprague-Dawley and Fischer 344 Rat. J Appl Toxicol. . 1986 Oct;6 (5) :349-56.|[2]J A Ferrendelli, et al. Inhibitory Effects of Anticonvulsant Drugs on Cyclic Nucleotide Accumulation in Brain. Ann Neurol. 1979 Jun;5 (6) :533-8.|[3]J G MILLICHAP, et al. Milontin: A New Drug in the Treatment of Petit Mal.Lancet. 1952 Nov 8;2 (6741) :907-10.|[4]S D Hall, et al. Characterization and inhibition of mephenytoin 4-hydroxylase activity in human liver microsomes. The JOURNAL OP PHARMAcOLOGY AND EXPERIMENTAL THERAPEUTICS
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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