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Phensuximide

CAT: 0804-HY-B1730-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B1730-01Size:5 mg
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Description
Phensuximide is an orally active succinimide antiepileptic and anticonvulsant agent. Phensuximide inhibits cyclic AMP and cyclic GMP accumulation in depolarized brain tissue. Phensuximide can be used for the study of seizure and petit mal[1][3].
CAS Number
86-34-0
UNSPSC
12352005
Hazard Statement
H302
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/phensuximide.html
Concentration
10mM
Purity
99.35
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C(C1=CC=CC=C1)C2)N(C)C2=O
Molecular Formula
C11H11NO2
Molecular Weight
189.21
Precautions
H302
References & Citations
[1]G O Rankin, et al. Urinary Tract Effects of Phensuximide in the Sprague-Dawley and Fischer 344 Rat. J Appl Toxicol. . 1986 Oct;6 (5) :349-56.|[2]J A Ferrendelli, et al. Inhibitory Effects of Anticonvulsant Drugs on Cyclic Nucleotide Accumulation in Brain. Ann Neurol. 1979 Jun;5 (6) :533-8.|[3]J G MILLICHAP, et al. Milontin: A New Drug in the Treatment of Petit Mal.Lancet. 1952 Nov 8;2 (6741) :907-10.|[4]S D Hall, et al. Characterization and inhibition of mephenytoin 4-hydroxylase activity in human liver microsomes. The JOURNAL OP PHARMAcOLOGY AND EXPERIMENTAL THERAPEUTICS
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched

Alternative Products

CatalogName
318483Phensuximide
A17882-5Phensuximide 5mg
A17882-50Phensuximide 50mg
A17882-2Phensuximide 2mg
A17882-100Phensuximide 100mg
A17882-25Phensuximide 25mg
A17882-10Phensuximide 10mg
A17882-10mM-DPhensuximide 10mM * 1mL in DMSO

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